It is a gastric proton pump inhibitor. Omeprazole is a substituted benzimidazole derivative acting on the final step of acid production & therefore controls intragastric acidity irrespective of stimulus. It markedly inhibits basal and stimulated gastric acid secretion. Thus it is antisecretory drug which is very effective for rapidly healing peptic ulcers & erosive oesophagitis & for reducing gastric acid hyper-secretion in patients with Zollinger-Ellison syndrome.
The drug acts by relaxing blood vessels so that blood passes through them more easily. This further helps to lower blood pressure.
Gastric ulcer: 20 mg once daily for 8 weeks in sever cases increase to 0 40 mg once daily
Duodenal ulcer: 20 mg once daily for 4 weeks.
Zollinger Ellison Syndrome: 60 mg once daily.
Maintenance therapy: 20 0120 mg adjusted to response.
Contra- Indications: Hypersensitivity, neonates
* Skin rash
Duodenal Ulcer (adults)
Prilosid is indicated for short-term treatment of active duodenal ulcer in adults. Most patients heal within four weeks. Some patients may require an additional four weeks of therapy.
Gastric Ulcer (adults)
Prilosid is indicated for short-term treatment (4-8 weeks) of active benign gastric ulcer in adults.
Concomitant Gastric Malignancy
Symptomatic response to therapy with omeprazole does not preclude the presence of gastric malignancy.
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole.
Clarithromycin is contraindicated in patients with a known hypersensitivity to any macrolide antibiotic.
Concomitant administration of clarithromycin with cisapride, pimozide, or terfenadine is contraindicated. There have been post-marketing reports of drug interactions when clarithromycin and/or erythromycin are co-administered with cisapride, pimozide, or terfenadine resulting in cardiac arrhythmias (QT prolongation, ventricular tachycardia, ventricular fibrillation, and torsades de pointes) most likely due to inhibition of hepatic metabolism of these drugs by erythromycin and clarithromycin. Fatalities have been reported. (Please refer to full prescribing information for clarithromycin before prescribing.)
Prilosid Capsules Strip of 10 Capsules
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Information for Health Care Professionals
*** Please consult local Prescribing Information for any product before use. This website is an international information resource for healthcare professionals with an interest in disease management. This website is not intended to replace the advice of a qualified healthcare professional. Above brand is a trademark of the Taj group of companies (Taj Pharmaceuticals Limited).
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The most common markets for this product include the following state . Please inquire with us if your state is not listed:
North India : Jammu & Kashmir ,Himachal Pradesh,Uttar Pradesh ,Uttaranchal , Punjab ,Haryana.
South India : Kerala, Karnataka ,Tamil Nadu,Andhra Pradesh.
East India : Assam ,Manipur, Meghalaya,West Bengal ,Orissa,Sikkim ,Mizoram, Tripura
West India : Goa ,Gujarat ,Rajasthan ,Maharashtra
Central India : Madhya Pradesh, Chattisgarh
Prilosid™ Capsules (Omeprazole) – TAJ PHARMA INDIA | Omeprazole is a substituted benzimidazole derivative acting on the final step of acid production & therefore controls intragastric acidity irrespective of stimulus. It markedly inhibits basal and stimulated gastric acid secretion.
Prilosid™ Capsules (Omeprazole) – TAJ PHARMA INDIA