Carbidopa, Levodopa and Entacapone Tablets 12.5mg+50mg+200mg

Carbidopa, Levodopa and Entacapone Tablets 12.5mg+50mg+200mg Technical Specification:

GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Carbidopa, Levodopa and Entacapone Tablets 12.5mg+50mg+200mg
B) Carbidopa, Levodopa and Entacapone Tablets 18.75mg+75mg+200mg
C) Carbidopa, Levodopa and Entacapone Tablets 37.5mg+150mg+200mg
D) Carbidopa, Levodopa and Entacapone Tablets 50mg+100mg+200mg
E) Carbidopa, Levodopa and Entacapone Tablets 50mg+200mg+200mg
F) Carbidopa, Levodopa and Entacapone Tablets 31.25mg+125mg+200mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Carbidopa, Levodopa and Entacapone Tablets 12.5mg+50mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….12.5mg
Levodopa USP………………………………………………50mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Quinizarine green ss

B) Carbidopa, Levodopa and Entacapone Tablets 18.75mg+75mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….18.75mg
Levodopa USP………………………………………………75mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Red oxide of iron

C) Carbidopa, Levodopa and Entacapone Tablets 37.5mg+150mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….37.5mg
Levodopa USP………………………………………………150mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Ponceau 4 R

D) Carbidopa, Levodopa and Entacapone Tablets 50mg+100mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….50mg
Levodopa USP………………………………………………100mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Titanium dioxide

E) Carbidopa, Levodopa and Entacapone Tablets 50mg+200mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….50mg
Levodopa USP………………………………………………200mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Indigo carmine aluminum lake

F) Carbidopa, Levodopa and Entacapone Tablets 31.25mg+125mg+200mg
Each film coated tablet contains:
Carbidopa USP
Equivalent to Carbidopa anhydrous………….31.25mg
Levodopa USP………………………………………………125mg
Entacapone USP……………………………………………200mg
Excipients…………………………………………………… q.s.
Colours: Lake of indigo carmine

THERAPEUTIC INDICATIONS:

Carbidopa, entacapone, and levodopa combination is used to treat Parkinson’s disease, sometimes called shaking palsy. Parkinson’s disease is a disorder of the central nervous system (brain and spinal cord).

CAUTION & WARNING:

CAUTION: Read enclosed leaflet before use.
Keep medicine out of reach of children.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.

Warning: To be sold by retail on the prescription of a Neurologist only.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].
Dispense in tight container.
Dosage: As directed by the Neurologist.

Attach dispensing label as per end country.

Introduction to Carbidopa, Levodopa and Entacapone Tablets 12.5mg+50mg+200mg

Carbidopa, Levodopa, and Entacapone Tablets 12.5mg+50mg+200mg are a combination medication commonly prescribed for managing Parkinson’s disease, a progressive neurodegenerative disorder characterized by tremors, rigidity, and impaired movements. This therapeutic combination aims to enhance the effectiveness of Parkinson’s treatment by addressing various symptoms and improving patients’ quality of life.

What Are These Tablets and Their Uses?

This medication combines three active ingredients:

• Carbidopa (12.5mg): Prevents the breakdown of Levodopa before it reaches the brain, increasing its effectiveness.
• Levodopa (50mg): The primary drug that converts into dopamine in the brain, alleviating motor symptoms.
• Entacapone (200mg): A COMT inhibitor that prolongs the effect of Levodopa by preventing its breakdown.

The demand for these tablets is rising globally due to the increasing prevalence of Parkinson’s disease, especially in aging populations across North America, Europe, Asia, and Africa. Indian pharmaceutical companies like Taj Pharma have become global leaders in manufacturing and exporting high-quality formulations, including this vital combination.

Global Demand

The global Parkinson’s disease treatment market is projected to grow significantly, driven by rising awareness, better diagnostic techniques, and the availability of effective medications like Carbidopa, Levodopa, and Entacapone Tablets 12.5mg+50mg+200mg. India’s role as a manufacturing hub for WHO-GMP-certified medicines makes it the preferred sourcing destination for international buyers.

In-Depth Details for Importers, Exporters & Buyers

Regulatory Documentation and Certifications

Taj Pharma provides comprehensive regulatory support, including:

• Certificates of Analysis (COA)
• WHO-GMP certification
• EU-GMP compliance certificates
• Certificate of Pharmaceutical Product (COPP)
• Detailed CTD Dossier for easy registration in target countries

These documents streamline import procedures, ensuring compliance with international standards and facilitating quick market entry.

Custom Packaging & Labeling

Customizable packaging solutions are available to meet regional regulatory and branding requirements. Labels can be translated into local languages, and packing options include bottles, blisters, or cartons designed to preserve stability and facilitate distribution.

Shelf-life, Storage, and Dosage Form

• Shelf-life: Typically 2-3 years under optimal storage conditions.
• Storage Conditions: Store in a cool, dry place, protected from light.
• Dosage Form: Film-coated, oval, white tablets available in various pack sizes tailored to customer needs.

Export Certifications and Target Markets

Taj Pharma holds essential certifications such as WHO-GMP, EU-GMP, and ISO, permitting export to over 20 countries, including the USA, UK, Canada, Australia, Middle East, and African nations. Their robust logistics network ensures timely delivery and consistent supply.

Target Countries & Export Markets

The primary export markets include North America, Europe, Asia, Africa, and the Middle East. Their strategic partnerships and compliance standards make Taj Pharma a trusted supplier across these regions.

Why Taj Pharma Is the Most Trusted Manufacturer & Exporter

1. State-of-the-Art Manufacturing Facilities

Located in Vapi, Gujarat, and Mumbai, Maharashtra, Taj Pharma operates cutting-edge manufacturing plants that adhere strictly to WHO-GMP standards. This guarantees the production of pure, safe, and effective Carbidopa, Levodopa, and Entacapone Tablets 12.5mg+50mg+200mg.

2. Competitive Pricing & Quality Assurance

Taj Pharma balances affordability with high quality. Their rigorous quality control processes—including validation, stability testing, and batch testing—ensure each lot meets international standards, providing consistent efficacy.

3. Extensive Global Presence & Supply Chain Support

With a presence in over 20 countries, Taj Pharma offers reliable supply chain management, ensuring that international buyers receive their orders on time, every time.

4. Leading Manufacturer & PCD Franchise Provider

Taj Pharma is recognized as a top manufacturer, exporter, and supplier of Carbidopa, Levodopa, and Entacapone Tablets 12.5mg+50mg+200mg in India. They also offer PCD Pharma franchise opportunities to entrepreneurs worldwide, empowering them to establish trusted brands.

5. Certifications & Standards

All products are manufactured under strict adherence to WHO-GMP, EU-GMP, and ISO standards, ensuring global acceptance and regulatory compliance.

Technical Product Specification Table

Call to Action

Are you seeking a reliable, cost-effective, and WHO-GMP-certified Carbidopa, Levodopa, and Entacapone Tablets 12.5mg+50mg+200mg supplier? Partner with Taj Pharma—India’s leading manufacturer and exporter. Contact us today for bulk orders, franchise opportunities, or strategic collaborations.

Email: info@tajpharma.com
Phone: +9122-2634 1274
Website: www.tajpharma.com

Top 10 FAQs

1. What is the primary use of these tablets?

They are used to manage Parkinson’s disease symptoms by increasing dopamine levels in the brain, reducing motor symptoms like tremors and rigidity.

2. Are these tablets safe during pregnancy?

They generally have good safety data during pregnancy and are often considered first-line treatment, but always consult a healthcare professional before use.

3. What are common side effects?

Possible side effects include nausea, dizziness, orthostatic hypotension, and involuntary movements. Allergic reactions such as skin rash, itching, swelling, or hives may also occur.

4. Can these tablets cause drowsiness?

Yes, some patients may experience drowsiness or falling asleep during daily activities. Caution is advised when performing tasks requiring alertness.

5. How long should I take these medications?

Typically, Parkinson’s disease treatment is long-term or lifelong, depending on disease progression and doctor’s recommendation.

6. Are there any drug interactions?

Yes, consult your doctor regarding interactions with other medications, especially antidepressants, antipsychotics, or other anti-Parkinsonian drugs.

7. Can I stop taking these tablets suddenly?

No. Abrupt discontinuation may worsen symptoms or cause neuroleptic malignant syndrome. Always follow your doctor’s guidance.

8. What should I do if I miss a dose?

Take it as soon as you remember, but if close to the next dose, skip the missed dose and continue with your regular schedule. Do not double doses.

9. Are there any dietary restrictions?

Limit high-protein foods around dosing times, as they may interfere with absorption.

10. Can elderly patients use these tablets?

Yes, but dosage adjustments may be necessary, and close monitoring is recommended.