Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets 150mg+75mg+400mg+275mg

Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets 150mg+75mg+400mg+275mg Technical specification:

GENERIC NAME OF THE MEDICINAL PRODUCT:

• Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets 
• Rifampicin + Isoniazid + Ethambutol Hydrochloride Tablets
• Rifampicin + Isoniazid Tablets

QUALITATIVE AND QUANTITATIVE COMPOSITION:

• Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets
  Each film coated Tablet contains:
  Rifampicin IP………………………………..…150mg
  Isoniazid IP……………………………………..75mg
  Pyrazinamide IP………………………………400mg
  Ethambutol Hydrochloride IP………….275mg
  Excipients………………………………………q.s
  Colour: Sunset Yellow FCF
• Rifampicin + Isoniazid + Ethambutol Hydrochloride Tablets
  Each film coated Tablet contains:
  Rifampicin IP………………………………..…150mg
  Isoniazid IP……………………………………..75mg
  Ethambutol Hydrochloride IP………….275mg
  Excipients………………………………………q.s
  Colour: Sunset Yellow FCF
• Rifampicin + Isoniazid  Tablets
  Each film coated Tablet contains:
  Rifampicin USP………………………………..…300mg
  Isoniazid BP……………………………………..150mg
  Excipients………………………………………q.s
  Colour: Red Oxide of Iron & Titanium Dioxide USP

THERAPEUTIC INDICATIONS:

• This combination is used in the treatment of tuberculosis. rifampicin works by inactivating a bacterial enzyme (rna-polymerase) which is required by tb bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. together, they kill the bacteria and eradicate the infection. ethambutol, on the other hand works by slowing the growth of these bacteria.

CAUTION & WARNING:

• CAUTION:  Read enclosed leaflet before use. Keep medicine out of reach of children. tablets to be swallowed as a whole, and not to be chewed or crushed.
• WARNING: It is dangerous to take this preparation except in accordance with the  medical advice. Not to be sold by retail without the prescription of registered Medical Practitioner.

STORAGE & DOSAGE:

• Storage: Store at temperature not exceeding 30℃. Store in cool, dry & dark place.  Protect from Light & moisture.
• Dosage: As directed by physician.

Introduction to Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets 150mg+75mg+400mg+275mg

Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets 150mg+75mg+400mg+275mg is a first-line fixed-dose combination therapy for tuberculosis (TB). This essential formulation simplifies treatment, improves compliance, and significantly increases the chances of curing TB.

Each component plays a critical role:

• Rifampicin: Prevents bacterial RNA synthesis.

• Isoniazid: Inhibits cell wall synthesis.

• Pyrazinamide: Active in acidic environments, targeting latent TB bacteria.

• Ethambutol Hydrochloride: Prevents bacterial resistance by inhibiting cell wall formation.

Globally, TB remains a major health concern, particularly in Africa, South Asia, and Southeast Asia. According to WHO, millions of new TB cases are reported annually, creating strong global demand for reliable anti-TB medicine suppliers.

As a trusted Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Hydrochloride Tablets manufacturer in India, Taj Pharma meets this demand by supplying high-quality, affordable, and WHO-GMP-certified TB medicines to governments, NGOs, and global distributors.

In-Depth Details for Importers, Exporters & Buyers

For global buyers, selecting the right pharmaceutical partner goes beyond product quality—it includes regulatory compliance, packaging adaptability, documentation support, and international certifications.

Regulatory Documentation Provided

Taj Pharma ensures smooth global trade with complete documentation support:

• WHO-GMP, EU-GMP certifications

• Certificate of Pharmaceutical Product (COPP)

• Good Manufacturing Practices (GMP) compliance reports

• Certificate of Analysis (COA) per batch

• CTD/ACTD dossiers for registration

• Stability studies and bioequivalence data (if required)

Custom Packaging & Labeling

• Blister packs, strip packs, or bulk packs available

• Multi-language packaging for export markets

• Custom branding for PCD franchise partners

• Regulatory-compliant labeling as per importing country

Shelf-Life, Storage & Dosage Form

• Dosage Form: Film-coated tablet

• Strengths: 150mg + 75mg + 400mg + 275mg

• Shelf Life: 24–36 months

• Storage: Keep in a cool, dry place below 25°C; protect from light & moisture

Export Certifications

Taj Pharma operates with international compliance:

• WHO-GMP certified facility

• ISO 9001:2015 quality assurance

• EU-GMP standards for regulated markets

• COPP for free sale certifications

• CTD/ACTD dossiers for global registrations

Target Countries & Export Markets

Taj Pharma is a leading anti-tuberculosis medicine exporter with a strong presence in:

• South Asia (India, Bangladesh, Sri Lanka, Nepal, Pakistan)

• Africa (Nigeria, Kenya, Tanzania, South Africa, Ghana, Ethiopia)

• CIS nations (Uzbekistan, Kazakhstan, Russia)

• Latin America (Peru, Bolivia, Chile)

• Middle East (Iraq, UAE, Saudi Arabia)

• Southeast Asia (Myanmar, Vietnam, Philippines)

This global distribution network makes Taj Pharma a preferred partner for governments, NGOs, and pharma distributors.

Why Taj Pharma is the Most Trusted Manufacturer, Supplier & Exporter

1. State-of-the-Art Manufacturing Facilities

Based in Vapi, Gujarat, Taj Pharma’s WHO-GMP-compliant facility uses advanced manufacturing technology to produce high-quality TB medicines that meet international pharmacopeia standards (IP, BP, USP).

2. Affordable Pricing with Quality Assurance

As TB disproportionately affects low- and middle-income countries, Taj Pharma ensures affordable pricing without compromising on efficacy or safety. Each batch undergoes rigorous quality checks.

3. Global Presence & Supply Chain Reliability

With exports to over 40 countries, Taj Pharma guarantees timely supply, global regulatory compliance, and seamless logistics support for importers and distributors.

4. Top 20 Countries Exporting Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Tablets

Nigeria, Kenya, Ghana, South Africa, Tanzania, Uganda, Philippines, Vietnam, Myanmar, Sri Lanka, Nepal, UAE, Saudi Arabia, Iraq, Yemen, Kazakhstan, Uzbekistan, Peru, Bolivia, Chile

Technical Product Specification Table

If you are an importer, distributor, or government procurement agency searching for a trusted partner in anti-tuberculosis medicines, Taj Pharma is your best choice.

✅ WHO-GMP certified
✅ Affordable pricing
✅ Full export documentation support
✅ Strong global supply chain

📩 Contact Taj Pharma today for quotations, regulatory dossiers, or export partnerships.
🌐 Visit: www.tajpharma.com

Top 20 FAQs

1. What is this medicine used for?
It is used in the treatment of active tuberculosis (TB).

2. How should it be taken?
On an empty stomach, at the same time daily, as prescribed.

3. What are the common side effects?
Nausea, vomiting, lethargy, skin rash, joint pain, and liver issues.

4. Can it cause vitamin deficiency?
Yes, it may cause vitamin B6 deficiency. Doctors may prescribe supplements.

5. Why does it cause red/orange urine or tears?
Rifampicin causes harmless discoloration of body fluids.

6. Can I take antacids with this medicine?
Not within 2 hours, as antacids reduce absorption.

7. Is it safe in pregnancy?
Only under strict medical supervision.

8. How long is the treatment duration?
Generally 6 months, but duration may vary.

9. Does Taj Pharma provide regulatory support?
Yes, with CTD/ACTD dossiers and COPP.

10. Is liver monitoring necessary?
Yes, liver function tests are recommended before and during treatment.

11. Can it cause peripheral neuropathy?
Yes, tingling in hands/feet may occur. Vitamin B6 helps prevent this.

12. Is it safe for children?
Yes, in weight-based doses under medical guidance.

13. Does Taj Pharma export globally?
Yes, to 40+ countries worldwide.

14. Can this be used for drug-resistant TB?
No, this is for first-line TB treatment only.

15. What should I do if I miss a dose?
Take it as soon as possible; skip if near next dose.

16. Can alcohol be taken during treatment?
No, alcohol increases liver toxicity risk.

17. What is its shelf life?
24–36 months depending on packaging.

18. Does Taj Pharma provide bulk orders?
Yes, with customized packaging for bulk exporters.

19. Is it WHO-GMP certified?
Yes, Taj Pharma’s plant is WHO-GMP certified.

20. Why choose Taj Pharma?
Because Taj Pharma ensures affordability, global compliance, timely supply, and top-quality TB medicines.