Rifampicin 150mg, Isoniazid 75mg, Pyrazinamide 400mg & Ethambutol Hydrochloride 275mg Tablets Manufacturer in India

As a globally recognized pharmaceutical manufacturer, Taj Pharma stands as one of the most trusted producers and exporters of Rifampicin 150mg, Isoniazid 75mg, Pyrazinamide 400mg & Ethambutol Hydrochloride 275mg Tablets (Funfunati). Our advanced manufacturing facilities in Vapi, Gujarat maintain the highest quality and regulatory standards, ensuring consistent therapeutic efficacy and safety for tuberculosis (TB) patients worldwide.

These four essential anti-tuberculosis medicines combined into a single formulation play a critical role as a first-line treatment for active Mycobacterium tuberculosis infections. Taj Pharma supplies these high-quality tablets across India, Africa, LATAM, CIS, the Middle East, and various international health programs.


What Are Rifampicin, Isoniazid, Pyrazinamide & Ethambutol Tablets?

This fixed-dose combination is a cornerstone in global TB treatment protocols. It offers multi-drug coverage targeting the bacteria at different stages, preventing drug resistance and ensuring effective bacterial eradication.

Therapeutic Uses

This four-drug therapy is widely prescribed for:

  • Pulmonary tuberculosis
  • Extrapulmonary TB affecting the spine, kidneys, brain, lymph nodes, and other organs
  • Drug-sensitive TB treatment in adults and adolescents
  • Combination therapy under DOTS programs

The formulation should only be taken under the supervision of a qualified healthcare provider.


Why Taj Pharma Is the Leading Manufacturer in India

As a top-ranking Rifampicin + Isoniazid + Pyrazinamide + Ethambutol manufacturer and exporter, Taj Pharma ensures unmatched product quality and global compliance.

Key Manufacturing Strengths

  • WHO-GMP, ISO, and FDA-approved manufacturing facilities
  • State-of-the-art quality testing using validated analytical techniques
  • Fully compliant with Pharmacopoeial standards (IP/BP/USP)
  • High batch consistency and international-standard packaging
  • Strong supply chain network across PAN India, Africa, Middle East & Latin America

Our brand Funfunati is well-recognized among healthcare professionals for reliability and consistent clinical results.


Mechanism of Action – How the Combination Works

Each active ingredient is vital in targeting different aspects of TB bacteria survival:

  • Rifampicin 150mg – Stops bacterial RNA synthesis
  • Isoniazid 75mg – Inhibits cell wall formation
  • Pyrazinamide 400mg – Effective against intracellular dormant bacilli
  • Ethambutol 275mg – Prevents cell wall synthesis and controls resistance

Together, the combination ensures rapid killing of TB bacteria while preventing resistance development, making it the gold-standard first-line TB therapy.


Dosage and Administration

  • Must be taken on an empty stomach, preferably at the same time daily
  • Treatment typically extends from 2 to 6 months, depending on severity
  • Strict adherence is essential to prevent treatment failure or drug resistance

Healthcare professionals may recommend Vitamin B6 (Pyridoxine) supplementation to counter Isoniazid-induced neuropathy.


Side Effects and Safety Precautions

Like any anti-tuberculosis therapy, this combination may cause certain side effects, including:

  • Nausea, vomiting, abdominal discomfort
  • Hepatitis or liver enzyme elevation
  • Peripheral neuropathy (tingling, numbness)
  • Joint pain
  • Skin rashes
  • Visual disturbances from Ethambutol
  • Thrombocytopenic purpura
  • Lethargy or fatigue

Regular medical monitoring is advised—especially liver function tests.


Global Exporter of Anti-Tuberculosis Medicines

Taj Pharma is one of India’s most trusted exporters of Rifampicin + Isoniazid + Pyrazinamide + Ethambutol tablets. Our products are widely supplied to:

  • Government health schemes
  • International NGOs
  • Private hospitals
  • Tender-based supply chains
  • Pharmaceutical distributors

We offer bulk manufacturing, private labeling, and PCD Pharma Franchise opportunities across multiple regions.


Product Highlights – Why Clients Prefer Taj Pharma

  • Accurate dosage combination ensuring optimum patient compliance
  • Affordable pricing for large-scale government and institutional orders
  • Designed to meet WHO-recommended TB treatment guidelines
  • High bioavailability and stable formulation
  • Strong global reputation backed by years of excellence

Available Supply & Franchise Opportunities

PCD Pharma Franchise

Taj Pharma welcomes distributors, wholesalers, and PCD partners across:

  • PAN India
  • Mumbai & Maharashtra
  • Gujarat
  • South India
  • North-Eastern states

Contract Manufacturing (OEM)

We provide third-party manufacturing services for:

  • Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Tablets
  • Custom bulk orders for international markets
  • Private label anti-TB formulations

Your 1 Partner for High-Quality Anti-TB Medicines

As a top manufacturer and exporter, Taj Pharma continues to deliver excellence through innovation, quality, and global healthcare commitment.

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With Taj Pharma, healthcare providers and global distributors are assured of superior quality, timely delivery, and regulatory compliance.


Taj Pharma stands as a leading force in the manufacturing, exporting, and distribution of Rifampicin 150mg, Isoniazid 75mg, Pyrazinamide 400mg & Ethambutol Hydrochloride 275mg Tablets in India and worldwide. Trusted for quality, affordability, and international standards, Taj Pharma remains the first choice of global buyers seeking reliable anti-TB formulations.