Sacubitril & Valsartan Tablets 50mg Manufacturer Supplier in India

As a trusted pharmaceutical manufacturer in India, we at Taj Pharma take pride in being one of the most reputable and quality-driven producers of Sacubitril & Valsartan Tablets 50mg. Recognized globally for excellence, we provide consistent supply, export-grade quality, and WHO–GMP-certified manufacturing standards for international markets, including Africa, LATAM,the Middle East, CIS, Southeast Asia, and PAN India distribution.

Our Sacubitril & Valsartan Tablets 50mg (Sacubvaltaj) is manufactured with precision, ensuring therapeutic efficacy, safety, and global compliance—making Taj Pharma the preferred partner for importers, distributors, government tenders, and PCD franchise holders.


About Sacubitril & Valsartan Tablets 50mg (Sacubvaltaj)

Sacubitril & Valsartan is a fixed-dose combination medication used for the treatment of chronic heart failure (NYHA class II–IV). It improves heart function, reduces cardiovascular mortality, decreases hospitalization rates, and enhances overall cardiac performance.

Composition

  • Sacubitril 24mg
  • Valsartan 26mg

Together, the combination belongs to ARNI (Angiotensin Receptor–Neprilysin Inhibitor) class, ensuring dual benefits:

  • Enhances natriuretic peptide activity
  • Blocks angiotensin II receptors
  • Reduces strain on the heart
  • Controls hypertension
  • Improves patient longevity

Mechanism of Action

1. Sacubitril (Neprilysin Inhibitor)

Sacubitril prevents neprilysin-mediated breakdown of:

  • Natriuretic peptides
  • Bradykinin
  • Adrenomedullin

This enhances vasodilation, natriuresis, and diuresis, significantly reducing cardiac workload.

2. Valsartan (ARB)

Valsartan blocks AT1 receptors, preventing:

  • Vasoconstriction
  • Aldosterone release
  • Sodium retention

This helps improve cardiac output and normalize blood pressure.


Therapeutic Benefits of Sacubitril & Valsartan Tablets 50mg

  • Reduces the risk of hospitalization due to heart failure
  • Improves left ventricular ejection fraction
  • Controls systolic and diastolic blood pressure
  • Minimizes the risk of cardiovascular death
  • Enhances quality of life in chronic heart failure patients
  • Effective even in long-standing heart failure cases

Why Taj Pharma Is the No.1 Manufacturer of Sacubitril & Valsartan Tablets 50mg?

1. WHO–GMP & EU-GMP Standard Facilities

We manufacture Sacubitril & Valsartan Tablets in ultra-modern plants equipped with:

  • Automated batch reactors
  • High-speed tablet compression lines
  • ISO-certified testing laboratories
  • Strict microbiological controls

2. Highest Quality APIs

We source APIs only from certified suppliers, ensuring:

  • Maximum purity
  • Excellent assay value
  • Enhanced bioavailability

3. Large-Scale Production Capacity

Taj Pharma produces millions of tablets monthly to meet global demand from:

  • Government procurement agencies
  • Tender suppliers
  • Pharmaceutical distributors
  • Generic medicine exporters

4. 100% Regulatory Compliance

Our documentation support includes:

  • COA
  • MOA
  • COPP
  • Stability data
  • Site master file
  • GMP certifications

5. Trusted Exporter to 40+ Countries

We have established a strong presence in:
✓ Africa
✓ Middle East
✓ LATAM
✓ CIS
✓ Southeast Asia
✓ Europe (regulated semi-regulated markets)


Dosage & Administration

  • Usually taken twice daily
  • Can be taken with or without food
  • Should be continued even if symptoms improve
  • Dose adjusted based on patient’s renal, hepatic, and cardiovascular profile

Do not discontinue medication abruptly without consulting a physician.


Side Effects

Commonly observed side effects include:

  • Low blood pressure (hypotension)
  • Dizziness
  • High potassium levels (hyperkalemia)
  • Impaired renal function
  • Dry cough
  • Fatigue

Patients should rise slowly from sitting or lying position to prevent dizziness.


Precautions

Before starting Sacubitril & Valsartan, patients must inform their doctor if they have:

  • Kidney disease
  • Liver impairment
  • History of angioedema
  • Electrolyte imbalance
  • Pregnancy or breastfeeding status

Avoid combining this medication with ACE inhibitors or aliskiren.


PAN India Supplier & Global Exporter

We supply Sacubitril & Valsartan Tablets 50mg across:

  • Mumbai, Maharashtra
  • Vapi, Gujarat
  • Delhi NCR
  • Chennai, Hyderabad, Bengaluru

International shipments are handled with:

  • Temperature-controlled packaging
  • 100% product traceability
  • Strong export logistics

Sacubitril & Valsartan Tablets 50mg – Available Product Variants by Taj Pharma

We also offer:

  • PCD Pharma franchise
  • Contract manufacturing services
  • Private label services

Applications in Healthcare Systems

Sacubitril & Valsartan is widely used in:

  • Cardiology hospitals
  • Government healthcare programs
  • Medical colleges
  • Public sector tenders
  • Emergency cardiac care management

Packaging & Shelf Life

Taj Pharma provides premium packaging options:

  • Alu-Alu blister packs
  • HDPE bottles
  • Export-compliant cartons

All batches undergo stability testing to ensure a shelf life of 24–36 months.


Why Global Buyers Prefer Taj Pharma?

  • Zero deviation in quality
  • Seamless export documentation
  • On-time delivery commitment
  • Highly competitive pricing
  • Customizable MOQ for importers
  • Dedicated technical support
  • Transparent business ethics

As one of India’s most reliable manufacturers, we ensure that Sacubitril & Valsartan Tablets 50mg meet the highest international standards for safety, potency, and consistency. Taj Pharma stands as the first choice for global buyers seeking trusted ARNI formulations with guaranteed regulatory support.