Welcome to Taj Pharma India Ltd — Redefining Excellence in Pharmaceutical Manufacturing

Taj Pharma India Ltd is a leading name in the pharmaceutical industry, delivering innovation, reliability, and uncompromised quality. Strategically located near Vapi, Gujarat, our state-of-the-art oral solid dosage (OSD) facility in Sarigam GIDC is built to meet the highest international regulatory standards, including WHO-GMP, with PICS and EU GMP certifications in progress.

Production Capacity

  • Tablet Manufacturing Capacity: 120 million tablets per month
  • Designed for high-throughput, flexibility, and batch-size versatility — from clinical trial scale to full commercial volumes.

Tablet Manufacturing: Technical Overview

Key Manufacturing Operations:

  1. Granulation
    • Dry Granulation (Roller Compaction for moisture-sensitive APIs)
    • Wet Granulation using high-shear mixers and fluid bed processors (FBD)
  2. Blending
    • Use of bin blenders and octagonal blenders to ensure uniformity of API and excipients.
  3. Compression
    • Equipped with high-speed rotary tablet compression machines (e.g., Korsch, Fette, Cadmach) with turret changeovers for varied tablet formats.
    • Compression under strict environmental and weight variation controls.
  4. Coating
    • Automatic coating machines (Glatt, Neocota) with optimized spray drying and air flow systems for:
      • Film coating
      • Sugar coating
      • Enteric coating
      • Controlled-release coatings
  5. Inspection & Packing
    • Online tablet inspection systems with metal detection
    • Fully automated blister packing (PVC/Alu, Alu/Alu)
    • Strip packing, bottle filling, and serialization-enabled secondary packing lines

Types of Tablets Manufactured at Taj Pharma

Taj Pharma’s advanced production lines are capable of manufacturing a diverse range of tablet formulations, including but not limited to:

Tablet TypeTechnical Features
Effervescent TabletsRapid disintegration in water; contains acid-base pair; moisture-sensitive formulation
Chewable TabletsDesigned for pediatric or geriatric use; pleasant taste; direct compression
Buccal TabletsDesigned for placement in the buccal pouch; slow release; avoids first-pass metabolism
Coated TabletsFilm or sugar-coated for taste masking or protection from light/moisture
Enteric-coated TabletspH-sensitive polymers (e.g., Eudragit L/S) for intestinal release
Prolonged Release TabletsMatrix or reservoir systems; hydrophilic polymers; extended plasma drug profile
Controlled Release TabletsOsmotic systems, ion-exchange resins, multi-layer tablets for controlled drug delivery
Disintegrating TabletsSuperdisintegrants (Crospovidone, Sodium starch glycolate) for rapid oral disintegration
Sublingual TabletsRapidly dissolving under tongue; high bioavailability via sublingual mucosa

Technology and Compliance

  • HVAC & Environmental Controls: ISO Class 8 (Grade D) for general manufacturing; ISO Class 7 (Grade C) for critical zones
  • Water Systems: Purified Water (PW) and Water for Injection (WFI) loops with online TOC and conductivity monitoring
  • In-Process Control (IPC): Real-time checks for weight, hardness, thickness, disintegration, friability
  • Quality Management System: Fully validated systems with documentation as per ICH Q7 & WHO TRS

Certifications & Approvals

  • Existing: WHO-GMP, ISO 9001:2015
  • Upcoming: PICS, EU-GMP
  • Compliance Standards: ICH, USP, BP, Ph. Eur., Schedule M

Therapeutic Segments Covered

Taj Pharma’s tablet portfolio spans across therapeutic areas including:

  • Cardiology
  • CNS & Psychiatry
  • Gastroenterology
  • Antibiotics & Antivirals
  • Endocrinology (Diabetes/Thyroid)
  • Anti-HIV / ARVs
  • Nutraceuticals & Supplements

Therapeutic Segments in Technical Depth

Taj Pharma’s Sarigam OSD facility delivers a diverse and robust range of oral solid dosage (OSD) forms across multiple therapeutic areas. With end-to-end formulation development, regulatory support, and large-scale production, Taj Pharma caters to global markets with WHO-GMP-compliant manufacturing and dossier-ready products.

1. Cardiology Segment

Overview:

Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality globally. Taj Pharma formulates cardiovascular drugs focused on hypertension, angina, heart failure, dyslipidemia, and antiplatelet therapies. Tablets are manufactured in immediate, extended, and modified-release formats.

Technical Aspects:

  • Compression: High-pressure rotary machines for uniformity
  • Release Kinetics: Matrix polymers (HPMC, EC) for sustained-release
  • Stability: Accelerated zone IVB testing for tropical climates

Top 5 Molecules:

Molecule NamePharmacological ClassStrengths Available
AmlodipineCalcium Channel Blocker (CCB)2.5mg, 5mg, 10mg
AtorvastatinHMG-CoA Reductase Inhibitor10mg, 20mg, 40mg
RamiprilACE Inhibitor2.5mg, 5mg, 10mg
ClopidogrelP2Y12 Inhibitor (Antiplatelet)75mg, 150mg
Bisoprolol FumarateBeta-1 Selective Blocker2.5mg, 5mg, 10mg

2. CNS & Psychiatry

Overview:

Central Nervous System (CNS) formulations address disorders like depression, schizophrenia, anxiety, epilepsy, and bipolar disorder. Taj Pharma offers high-stability formulations with specialized coating to maintain drug integrity and bioavailability.

Technical Aspects:

  • ODTs for improved compliance
  • Modified-release tablets for mood stabilizers
  • Low-dose uniformity and narrow therapeutic index (NTI) handling

Top 5 Molecules:

Molecule NameClassStrengths Available
OlanzapineAtypical Antipsychotic2.5mg, 5mg, 10mg, 15mg
EscitalopramSSRI Antidepressant5mg, 10mg, 20mg
Sodium ValproateAnticonvulsant / Mood Stabilizer200mg, 300mg, 500mg
Quetiapine FumarateAtypical Antipsychotic25mg, 100mg, 200mg, 400mg
RisperidoneAtypical Antipsychotic0.5mg, 1mg, 2mg, 4mg

3. Gastroenterology

Overview:

This segment targets acid reflux, ulcers, motility disorders, and IBS. Taj Pharma’s formulations ensure acid-stable delivery, enteric protection, and targeted intestinal release.

Technical Aspects:

  • Enteric coating (Eudragit® L100/S100) for PPIs
  • Multilayer tablets for dual-action therapy
  • Stability under acid/base conditions

Top 5 Molecules:

Molecule NameClassStrengths Available
PantoprazoleProton Pump Inhibitor (PPI)20mg, 40mg (EC)
RabeprazolePPI10mg, 20mg (EC)
DomperidoneProkinetic/Dopamine Antagonist10mg, 20mg
MesalamineAnti-inflammatory (IBD)400mg, 800mg (EC, SR)
Itopride HClGastroprokinetic50mg, 100mg

4. Antibiotics & Antivirals

Overview:

Formulations target bacterial infections, respiratory tract infections, and select viral conditions. Taj Pharma ensures API compatibility, stability against hydrolysis, and resistance to cross-contamination.

Technical Aspects:

  • Moisture control during granulation of β-lactams
  • Compatibility studies for antibiotic-combo tablets
  • Rapid disintegration for pediatric formats

Top 5 Molecules:

Molecule NameClassStrengths Available
Amoxicillin + ClavulanateBroad-spectrum Penicillin500/125mg, 875/125mg
AzithromycinMacrolide Antibiotic250mg, 500mg
CefiximeCephalosporin Antibiotic100mg, 200mg
LevofloxacinFluoroquinolone250mg, 500mg, 750mg
OseltamivirAntiviral (Influenza)30mg, 45mg, 75mg

5. Endocrinology (Diabetes / Thyroid)

Overview:

Formulations for Type 2 Diabetes Mellitus, thyroid disorders, and metabolic syndromes. Special attention is given to bi-layer, prolonged release, and fixed-dose combination (FDC) tablets.

Technical Aspects:

  • Hydrophilic matrix systems (e.g., HPMC) for metformin SR
  • Film-coated tablets for thyroid stability (light-sensitive)
  • FDC bioequivalence assurance

Top 5 Molecules:

Molecule NameClassStrengths Available
Metformin HCl (IR/SR)Biguanide500mg, 750mg, 1000mg
GlimepirideSulfonylurea1mg, 2mg, 4mg
SitagliptinDPP-4 Inhibitor25mg, 50mg, 100mg
Levothyroxine SodiumSynthetic Thyroid Hormone25mcg – 150mcg
Vildagliptin + MetforminDPP-4i + Biguanide Combo50/500mg, 50/1000mg

6. Anti-HIV / ARVs

Overview:

Taj Pharma offers WHO-prequalified formulations in the antiretroviral (ARV) domain. These are designed to be stable in Zone IVB climates and comply with PEPFAR and Global Fund requirements.

Technical Aspects:

  • FDC tablets for patient convenience
  • Low-dose high-potency APIs
  • Strict segregation and containment protocols

Top 5 Molecules:

Molecule NameClassStrengths Available
Tenofovir Disoproxil Fumarate (TDF)NRTI300mg
LamivudineNRTI150mg, 300mg
EfavirenzNNRTI600mg
DolutegravirINSTI50mg
TDF + Lamivudine + Efavirenz (FDC)Triple Combination300/300/600mg

7. Nutraceuticals & Supplements

Overview:

Formulations support general wellness, immunity, metabolism, and therapeutic support (e.g., bone health, cognitive support). Products are tailored to effervescent, chewable, and sustained-release formats for better bioavailability.

Technical Aspects:

  • Effervescent technology for high-dose water-soluble vitamins
  • Chewable tablets with natural flavors
  • Disintegration testing for gut absorption optimization

Top 5 Molecules:

Molecule NameCategoryFormulation Type
Vitamin D3 (Cholecalciferol)Bone & Immunity60,000 IU chewable/soft tabs
Zinc + Vitamin CImmunityEffervescent/Chewable
Iron + Folic AcidHematinicFilm-coated tablets
Coenzyme Q10Cardioprotective AntioxidantSR tablets
Biotin + Collagen + ALA ComplexSkin/Nerve HealthMultilayered or coated tabs

Taj Pharma India Ltd’s tablet product line is distinguished by robust formulation science, stringent regulatory compliance, and diverse delivery technologies. From anti-infectives to lifestyle disease therapeutics and nutraceutical innovations, Taj Pharma continues to advance pharmaceutical access and excellence globally.


Global Presence

Taj Pharma’s tablet formulations are registered and exported across more than 40 countries in regions such as:

  • Africa
  • LATAM
  • Southeast Asia
  • CIS
  • Middle East
  • EU (awaiting approval)

Taj Pharma India Ltd is not just a tablet manufacturer — it is a partner in global health. With a commitment to cutting-edge technology, regulatory compliance, and efficient scale-up, Taj Pharma continues to set benchmarks in oral solid dosage manufacturing.